제품 > 항체 > 단일클론항체(mAb)

ABflo® 510 Rabbit anti-Human CD38 mAb (A26943)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human

Flow cytometry: 1X10^6 Hep G2 cells (negative control, left) and Daudi cells (right) were surface-stained with ABflo® 510 Rabbit anti-Human CD38 mAb (A26943, 5 μl/Test, orange line) or ABflo® 510 Rabbit IgG isotype control (5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).

Flow cytometry: 1X10^6 Daudi cells were surface-stained with ABflo® 510 Rabbit IgG isotype control (5 μl/Test, left) or ABflo® 510 Rabbit anti-Human CD38 mAb (A26943, 5 μl/Test, right).

Flow cytometry: 1X10^6 Human PBMC were surface-stained with ABflo® 510 Rabbit anti-Human CD38 mAb (A26943, 5 μl/Test, orange line) or ABflo® 510 Rabbit IgG isotype control (5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line). Cells in the gate were used for analysis.

Flow cytometry: 1X10^6 Human PBMC were surface-stained with ABflo® 510 Rabbit IgG isotype control (5 μl/Test, left) or ABflo® 510 Rabbit anti-Human CD38 mAb (A26943, 5 μl/Test, right).

Overview

Product name	ABflo® 510 Rabbit anti-Human CD38 mAb
Catalog No.	A26943
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG
CloneNo.	ARC5131-01-ABf510

Background

The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.

Immunogen information

Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 43-300 of human CD38 (P28907).
Sequence	VPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI
Gene ID
Swiss Prot
Synonyms	ADPRC1; cADPR1; ADPRC 1
Calculated MW	13kDa/34kDa
Observed MW

Applications

Reactivity	Human
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	FC 5 μl per 10^6 cells in 100 μl volume
Storage buffer	Store at 2-8℃. Avoid freeze. Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Key application	Flow Cytometry
Positive samples
Cellular location	Membrane, Single-pass type II membrane protein, basolateral plasma membrane, cell surface, extracellular exosome, nucleus, plasma membrane.

Documents

Certificate of Compliance

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Research Area

ABflo® 510 Rabbit anti-Human CD38 mAb images

Flow CytoMetry - ABflo® 510 Rabbit anti-Human CD38 mAb (A26943)

Flow cytometry: 1X10^6 Daudi cells were surface-stained with ABflo® 510 Rabbit IgG isotype control (5 μl/Test, left) or ABflo® 510 Rabbit anti-Human CD38 mAb (A26943, 5 μl/Test, right).

Flow CytoMetry - ABflo® 510 Rabbit anti-Human CD38 mAb (A26943)

Flow cytometry: 1X10^6 Human PBMC were surface-stained with ABflo® 510 Rabbit IgG isotype control (5 μl/Test, left) or ABflo® 510 Rabbit anti-Human CD38 mAb (A26943, 5 μl/Test, right).

* For research use only. Not for therapeutic or diagnostic purposes.