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BCL2A1 Rabbit pAb (A0134)

Publications (2) Datasheet

Tested applications:WBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibitionReactivity:Human

ABclonal:Immunofluorescence - BCL2A1 Rabbit pAb (A0134)

Immunofluorescence analysis of Jurkat cells using BCL2A1 Rabbit pAb (A0134) at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.

ABclonal:Immunofluorescence - BCL2A1 Rabbit pAb (A0134)

Immunofluorescence analysis of THP-1 cells using BCL2A1 Rabbit pAb (A0134) at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.

Overview

Product nameBCL2A1 Rabbit pAb
Catalog No.A0134
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 70-150 of human BCL2A1 (NP_004040.1).
SequenceLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEP
Gene ID
Swiss Prot
SynonymsGRS; ACC1; ACC2; BFL1; ACC-1; ACC-2; HBPA1; BCL2L5
Calculated MW20kDa
Observed MWRefer to figures
ReactivityHuman
Tested applicationsWBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibition
Recommended dilution
  • WB 1:500 - 1:2000
  • IF/ICC 1:50 - 1:200
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Key applicationWestern blotting    Immunofluorescence    
Positive samples
Cellular locationCytoplasm
Customer validation

WB(Homo sapiens)

Documents

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ABclonal:Immunofluorescence - BCL2A1 Rabbit pAb (A0134)}

Immunofluorescence - BCL2A1 Rabbit pAb (A0134)

Immunofluorescence analysis of Jurkat cells using BCL2A1 Rabbit pAb (A0134) at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
ABclonal:Immunofluorescence - BCL2A1 Rabbit pAb (A0134)}

Immunofluorescence - BCL2A1 Rabbit pAb (A0134)

Immunofluorescence analysis of THP-1 cells using BCL2A1 Rabbit pAb (A0134) at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.

* For research use only. Not for therapeutic or diagnostic purposes.

Publishing research using A0134? Please let us know so that we can cite the reference in this datasheet.

Secondary Antibodies (26)