제품 > 항체 > 단일클론항체(mAb)

Mannose Receptor/CD206 Rabbit mAb (A11192)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human, Mouse

Western blot analysis of lysates from mouse lung, using Mannose Receptor/CD206 Rabbit mAb (A11192) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.

Overview

Product name	Mannose Receptor/CD206 Rabbit mAb
Catalog No.	A11192
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG
CloneNo.	ARC0538

Background

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.

Immunogen information

Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1357-1456 of human Mannose Receptor/CD206 (P22897).
Sequence	RPKIIDAKPTHELLTTKADTRKMDPSKPSSNVAGVVIIVILLILTGAGLAAYFFYKKRRVHLPQEGAFENTLYFNSQSSPGTSDMKDLVGNIEQNEHSVI
Gene ID
Swiss Prot
Synonyms	MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1; Mannose Receptor/CD206
Calculated MW	166kDa
Observed MW	166kDa

Applications

Reactivity	Human, Mouse
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	WB 1:500 - 1:2000 ELISA Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Key application	Western blotting
Positive samples	Mouse lung
Cellular location	Cell membrane, Endosome membrane, Single-pass type I membrane protein.
Customer validation	WB(Homo sapiens, Mus musculus) IF(Mus musculus, Other)

Documents

Certificate of Compliance

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Lot number

Research Area

연구면역학 & 염증CDs

Mannose Receptor/CD206 Rabbit mAb images

Western blot - Mannose Receptor/CD206 Rabbit mAb (A11192)

* For research use only. Not for therapeutic or diagnostic purposes.

Product Protocols

References for Mannose Receptor/CD206 Rabbit mAb (A11192)

Product:

Mannose Receptor/CD206 Rabbit mAb

Journal:

Cell death discovery

Application:

IF:

7.1

Species:

Homo sapiens

PMID:

36681667

Title:

Cancer-associated fibroblast-secreted IGFBP7 promotes gastric cancer by enhancing tumor associated macrophage infiltration via FGF2/FGFR1/PI3K/AKT axis - PMC

References for Mannose Receptor/CD206 Rabbit mAb (A11192)

Product:

Mannose Receptor/CD206 Rabbit mAb

Journal:

Clinical epigenetics

Application:

IF:

4.8

Species:

Mus musculus

PMID:

37951958

Title:

Histone deacetylase 3 deletion in alveolar type 2 epithelial cells prevents bleomycin-induced pulmonary fibrosis - PMC

References for Mannose Receptor/CD206 Rabbit mAb (A11192)

Product:

Mannose Receptor/CD206 Rabbit mAb

Journal:

Biochemical pharmacology

Application:

IF:

5.3

Species:

Homo sapiens

PMID:

37591448

Title:

MiR-146a-5p enrichment in small-extracellular vesicles of relapsed pediatric ALCL patients promotes macrophages infiltration and differentiation

References for Mannose Receptor/CD206 Rabbit mAb (A11192)

Product:

Mannose Receptor/CD206 Rabbit mAb

Journal:

Scientific reports

Application:

IF:

3.8

Species:

Mus musculus

PMID:

38233593

Title:

Periodontal ligament cells-derived exosomes promote osteoclast differentiation via modulating macrophage polarization - PMC

References for Mannose Receptor/CD206 Rabbit mAb (A11192)

Product:

Mannose Receptor/CD206 Rabbit mAb

Journal:

ACS nano

Application:

IF:

15.8

Species:

Mus musculus

PMID:

38266247

Title:

Bioactive Ceria Nanoenzymes Target Mitochondria in Reperfusion Injury to Treat Ischemic Stroke

References for Mannose Receptor/CD206 Rabbit mAb (A11192)

Product:

Mannose Receptor/CD206 Rabbit mAb

Journal:

Fish & shellfish immunology

Application:

IF:

4.1

Species:

Other

PMID:

38104695

Title:

The potential mechanism of concentrated mannan-oligosaccharide promoting goldfish's (Carassius auratus Linnaeus) resistance to Ichthyophthirius multifiliis invasion

References for Mannose Receptor/CD206 Rabbit mAb (A11192)

Product:

Mannose Receptor/CD206 Rabbit mAb

Journal:

Acta physiologica (Oxford, England)

Application:

IF:

6.4

Species:

Mus musculus

PMID:

38767438

Title:

Augmenter of liver regeneration knockout aggravates tubular ferroptosis and macrophage activation by regulating carnitine palmitoyltransferase1Ainduced lipid