Phospho-HDAC8-S39 Rabbit pAb (AP0360)

Datasheet

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human

Overview

Product name	Phospho-HDAC8-S39 Rabbit pAb
Catalog No.	AP0360
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen information

Immunogen	A phospho specific peptide corresponding to residues surrounding S39 of human HDAC8
Sequence	Email for sequence
Gene ID
Swiss Prot
Synonyms	HD8; WTS; RPD3; CDA07; CDLS5; KDAC8; MRXS6; HDACL1; Phospho-HDAC8-S39
Calculated MW	42kDa
Observed MW

Applications

Reactivity	Human
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	IF/ICC 1:100 - 1:200
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Key application	Immunofluorescence
Positive samples
Cellular location	Cytoplasm, Nucleus