제품 > 항체 > 단일클론항체(mAb)

ABflo® 488 Rabbit anti-Human IL-6R/CD126 mAb (A26723)

Datasheet

Tested applications:WBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibitionReactivity:Human

ABclonal:Flow CytoMetry - ABflo® 488 Rabbit anti-Human IL-6R/CD126 mAb (A26723)

Flow cytometry: 1X10^6 HeLa cells (negative control, left) and U266 cells (right) were intracellularly-stained with ABflo® 488 Rabbit anti-Human IL-6R/CD126 mAb (A26723, 2 μg/mL, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).

ABclonal:Flow CytoMetry - ABflo® 488 Rabbit anti-Human IL-6R/CD126 mAb (A26723)

Flow cytometry: 1X10^6 U266 cells were intracellularly-stained with ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo® 488 Rabbit anti-Human IL-6R/CD126 mAb (A26723, 5 μl/Test, right).

Overview

Product nameABflo® 488 Rabbit anti-Human IL-6R/CD126 mAb
Catalog No.A26723
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
CloneNo.ARC64301-ABflo488
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9.
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 20-358 of human IL-6R/CD126 (NP_000556.1).
SequenceLAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQD
Gene ID
Swiss Prot
SynonymsIL6Q; gp80; CD126; HIES5; IL-6R; IL6RA; IL6RQ; IL-1Ra; IL-6RA; IL6QTL; IL-6R-1
Calculated MW52kDa
Observed MW
ReactivityHuman
Tested applicationsWBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibition
Recommended dilution
  • FC (intra) 5 μl per 10^6 cells in 100 μl volume
Storage bufferStore at 2-8℃. Avoid freeze.
Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Key application
Positive samples
Cellular locationBasolateral cell membrane, Secreted, Single-pass type I membrane protein.

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ABclonal:Flow CytoMetry - ABflo® 488 Rabbit anti-Human IL-6R/CD126 mAb (A26723)}

Flow CytoMetry - ABflo® 488 Rabbit anti-Human IL-6R/CD126 mAb (A26723)

Flow cytometry: 1X10^6 HeLa cells (negative control, left) and U266 cells (right) were intracellularly-stained with ABflo® 488 Rabbit anti-Human IL-6R/CD126 mAb (A26723, 2 μg/mL, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).
ABclonal:Flow CytoMetry - ABflo® 488 Rabbit anti-Human IL-6R/CD126 mAb (A26723)}

Flow CytoMetry - ABflo® 488 Rabbit anti-Human IL-6R/CD126 mAb (A26723)

Flow cytometry: 1X10^6 U266 cells were intracellularly-stained with ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo® 488 Rabbit anti-Human IL-6R/CD126 mAb (A26723, 5 μl/Test, right).

* For research use only. Not for therapeutic or diagnostic purposes.

항체 (3)

ELISA 키트 (1)

재조합 단백질 (3)

제품 (3)

Secondary Antibodies (26)