제품 > 항체 > 다중클론항체(pAb)

DSG3/Desmoglein-3 Rabbit pAb (A25099)

Datasheet

Tested applications:WBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibitionReactivity:Human

ABclonal:Immunohistochemistry - DSG3/Desmoglein-3 Rabbit pAb (A25099)

Immunohistochemistry analysis of DSG3/Desmoglein-3 in paraffin-embedded human lung squamous carcinoma tissue tissue using DSG3/Desmoglein-3 Rabbit pAb (A25099) at a dilution of 1:100 (40x lens). High pressure antigen retrieval was performed with 0.01 M citrate buffer (pH 6.0) prior to IHC staining.

Overview

Product nameDSG3/Desmoglein-3 Rabbit pAb
Catalog No.A25099
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.
ImmunogenRecombinant Protein corresponding to a sequence within amino acids 50-615 of human DSG3/Desmoglein-3(NP_001935.2).
SequenceEWVKFAKPCREGEDNSKRNPIAKITSDYQATQKITYRISGVGIDQPPFGIFVVDKNTGDINITAIVDREETPSFLITCRALNAQGLDVEKPLILTVKILDINDNPPVFSQQIFMGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIVSQEPAGTPMFLLSRNTGEVRTLTNSLDREQASSYRLVVSGADKDGEGLSTQCECNIKVKDVNDNFPMFRDSQYSARIEENILSSELLRFQVTDLDEEYTDNWLAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKALDYEQLQSVKLSIAVKNKAEFHQSVISRYRVQSTPVTIQVINVREGIAFRPASKTFTVQKGISSKKLVDYILGTYQAIDEDTNKAASNVKYVMGRNDGGYLMIDSKTAEIKFVKNMNRDSTFIVNKTITAEVLAIDEYTGKTSTGTVYVRVPDFNDNCPTAVLEKDAVCSSSPSVVVSARTLNNRYTGPYTFALEDQPVKLPAVWSITTLNATSALLRAQEQIPPGVYHISLVLTDSQNNRCEMPRSLTLEVCQCDNRGICGTSYPTTSPGTRYGRPHSGR
Gene ID
Swiss Prot
SynonymsPVA; ABOLM; CDHF6; Desmoglein 3
Calculated MW108kDa
Observed MWRefer to figures
ReactivityHuman
Tested applicationsWBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibition
Recommended dilution
  • IHC-P 1:50 - 1:200
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Key applicationImmunohistochemistry    
Positive samples
Cellular locationCell junction, Cell membrane, Single-pass type I membrane protein, desmosome

Documents

Certificate of Compliance

To download a Certificate of Compliance, please enter your Lot number below:

Lot number

ABclonal:Immunohistochemistry - DSG3/Desmoglein-3 Rabbit pAb (A25099)}

Immunohistochemistry - DSG3/Desmoglein-3 Rabbit pAb (A25099)

Immunohistochemistry analysis of DSG3/Desmoglein-3 in paraffin-embedded human lung squamous carcinoma tissue tissue using DSG3/Desmoglein-3 Rabbit pAb (A25099) at a dilution of 1:100 (40x lens). High pressure antigen retrieval was performed with 0.01 M citrate buffer (pH 6.0) prior to IHC staining.

* For research use only. Not for therapeutic or diagnostic purposes.

항체 (5)

Secondary Antibodies (26)