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MMP14/MT1-MMP Rabbit pAb (A15691)

Datasheet

Tested applications:WBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibitionReactivity:Human

ABclonal:Immunofluorescence - MMP14/MT1-MMP Rabbit pAb (A15691)

Immunofluorescence analysis of U2OS cells using MMP14/MT1-MMPantibody (A15691) at dilution of 1:100. Blue: DAPI for nuclear staining.

Overview

Product nameMMP14/MT1-MMP Rabbit pAb
Catalog No.A15691
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 75-174 of human MMP14/MT1-MMP (NP_004986.1).
SequenceQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQ
Gene ID
Swiss Prot
SynonymsMMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1
Calculated MW66kDa
Observed MW
ReactivityHuman
Tested applicationsWBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibition
Recommended dilution
  • IF/ICC 1:50 - 1:200
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Key applicationImmunofluorescence    
Positive samples
Cellular locationCytoplasm, Melanosome, Membrane, Single-pass type I membrane protein

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ABclonal:Immunofluorescence - MMP14/MT1-MMP Rabbit pAb (A15691)}

Immunofluorescence - MMP14/MT1-MMP Rabbit pAb (A15691)

Immunofluorescence analysis of U2OS cells using MMP14/MT1-MMPantibody (A15691) at dilution of 1:100. Blue: DAPI for nuclear staining.

* For research use only. Not for therapeutic or diagnostic purposes.

항체 (3)

Secondary Antibodies (26)