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TSC2 Rabbit pAb (A16007)

Datasheet

Tested applications:WBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibitionReactivity:Human, Mouse, Rat

ABclonal:Immunofluorescence - TSC2 Rabbit pAb (A16007)

Immunofluorescence analysis of C6 cells using TSC2 Rabbit pAb (A16007) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining.

ABclonal:Immunofluorescence - TSC2 Rabbit pAb (A16007)

Immunofluorescence analysis of NIH/3T3 cells using TSC2 Rabbit pAb (A16007) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining.

Overview

Product nameTSC2 Rabbit pAb
Catalog No.A16007
Host speciesRabbit
Purification methodAffinity purification
IsotypeIgG
This gene is a tumor suppressor gene that encodes the growth inhibitory protein tuberin. Tuberin interacts with hamartin to form the TSC protein complex which functions in the control of cell growth. This TSC protein complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis.
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1531-1807 of TSC2 (NP_000539.2).
SequenceVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
Gene ID
Swiss Prot
SynonymsLAM; TSC4; PPP1R160; TSC2
Calculated MW201kDa
Observed MW
ReactivityHuman, Mouse, Rat
Tested applicationsWBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibition
Recommended dilution
  • IF/ICC 1:50 - 1:100
Storage bufferStore at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Key applicationImmunofluorescence    
Positive samples
Cellular locationCytoplasm, Membrane, Peripheral membrane protein

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ABclonal:Immunofluorescence - TSC2 Rabbit pAb (A16007)}

Immunofluorescence - TSC2 Rabbit pAb (A16007)

Immunofluorescence analysis of C6 cells using TSC2 Rabbit pAb (A16007) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
ABclonal:Immunofluorescence - TSC2 Rabbit pAb (A16007)}

Immunofluorescence - TSC2 Rabbit pAb (A16007)

Immunofluorescence analysis of NIH/3T3 cells using TSC2 Rabbit pAb (A16007) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining.

* For research use only. Not for therapeutic or diagnostic purposes.

항체 (4)

Secondary Antibodies (26)