제품 > 항체 > 단일클론항체(mAb)

[KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human, Mouse, Rat, Monkey

Western blot analysis of lysates from wild type (WT) and NF-kB p65/RelA knockout (KO) HeLa cells using NF-kB p65/RelA Rabbit mAb (A19653) at 1:10000 dilution incubated overnight at 4℃.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.

Western blot analysis of lysates from PC-12 cells using NF-kB p65/RelA Rabbit mAb (A19653) at 1:10000 dilution incubated overnight at 4℃.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.

Western blot analysis of various lysates using NF-kB p65/RelA Rabbit mAb (A19653) at 1:10000 dilution incubated overnight at 4℃.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s.

ABclonal:Immunohistochemistry - [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer tissue using NF-kB p65/RelA Rabbit mAb (A19653) at a dilution of 1:800 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.

Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue using NF-kB p65/RelA Rabbit mAb (A19653) at a dilution of 1:800 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.

Immunohistochemistry analysis of paraffin-embedded Mouse spleen tissue using NF-kB p65/RelA Rabbit mAb (A19653) at a dilution of 1:800 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.

Immunohistochemistry analysis of paraffin-embedded Rat spleen tissue using NF-kB p65/RelA Rabbit mAb (A19653) at a dilution of 1:800 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate Bufferr (pH 6.0) prior to IHC staining.

ABclonal:Immunofluorescence - [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Immunofluorescence analysis of NIH/3T3 cells using NF-kB p65/RelA Rabbit mAb (A19653) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining.

Immunofluorescence analysis of U-2 OS cells using NF-kB p65/RelA Rabbit mAb (A19653) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining.

ABclonal:Chromatin Immunoprecipitation - [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Chromatin immunoprecipitation was performed with 10 μg of cross-linked chromatin from HT-1080 cells treated by TNF-α (20 ng/ml) at 37℃ for 30 minutes, using 5 μg of NF-kB p65/RelA Rabbit mAb antibody (A19653) and Rabbit IgG isotype control (AC042). The enrichment of immunoprecipitated DNA at different genomic loci was examined by quantitative PCR. The histogram compares the ratio of the immunoprecipitated DNA to the input at given loci.

Review

Overview

Product name	[KO Validated] NF-kB p65/RelA Rabbit mAb
Catalog No.	A19653
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG
CloneNo.	ARC51086

Background

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Immunogen information

Immunogen	A synthetic peptide corresponding to a sequence within amino acids 450-551 of human NF-κB p65 (Q04206).
Sequence	LGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFSALLSQISS
Gene ID
Swiss Prot
Synonyms	p65; CMCU; NFKB3; AIF3BL3; NF-kB p65/RelA
Calculated MW	60kDa
Observed MW	65kDa

Applications

Reactivity	Human, Mouse, Rat, Monkey
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	WB 1:5000 - 1:20000 IHC-P 1:500 - 1:2000 IF/ICC 1:50 - 1:200 ELISA Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. ChIP 5μg antibody for 10μg-15μg of Chromatin
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% sodium azid, 0.05% BSA, 50% glycerol, pH7.3.
Key application	Western blotting Immunohistochemistry Immunofluorescence
Positive samples	PC-12, Mouse spleen, Mouse lung, HeLa, PC-12, COS-7, NIH/3T3
Cellular location	Cytoplasm, Nucleus.
Customer validation	(RPMI-8226、PC-3、HepG2、Hela、U2-OS、Jurkat、MOLT-4) WB(Mus musculus, Homo sapiens, Rattus norvegicus, pearl oyster, Mus musculus, Sus scrofa, Rattus norvegicus, Danio rerio) IF(Homo sapiens, Rattus norvegicus, Mus musculus, Mus musculus ) IHC(Rattus norvegicus) IHC(Mus musculus) FC(Homo sapiens) IF(Rattus norvegicus, Mus musculus, Rattus norvegicus) IP(Mus musculus ) ELISA(Mus musculus) WB(Mus musculus) ChIP(Mus musculus) RT-PCR(Rattus norvegicus) WB(Rattus norvegicus, Drosophila melanogaster, Mus musculus) IP(Homo sapiens,Mus musculus) Co-IP(Drosophila melanogaster)

Documents

Certificate of Compliance

To download a Certificate of Compliance, please enter your Lot number below:

Lot number

Research Area

[KO Validated] NF-kB p65/RelA Rabbit mAb images

Western blot - [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Immunohistochemistry - [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Immunofluorescence - [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Chromatin Immunoprecipitation - [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

* For research use only. Not for therapeutic or diagnostic purposes.

Submit an review for A19653

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Reviews List

Product Protocols

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Inflammation

Application:

IF:

4.09

Species:

Mus musculus

PMID:

34341910

Title:

LncRNA H19 Mitigates Oxidized Low-Density Lipoprotein Induced Pyroptosis via Caspase-1 in Raw 264.7 Cells

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

J Nat Med

Application:

IF:

2.343

Species:

Mus musculus

PMID:

32761488

Title:

Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Life Sci

Application:

IF:

5.037

Species:

Homo sapiens

PMID:

32971102

Title:

PIGU promotes hepatocellular carcinoma progression through activating NF-κB pathway and increasing immune escape

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Front Pharmacol

Application:

IF:

5.81

Species:

Homo sapiens

PMID:

33708105

Title:

Transcriptome Analysis of the Inhibitory Effect of Sennoside A on the Metastasis of Hepatocellular Carcinoma Cells

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Cell Death Discov

Application:

IF:

5.241

Species:

Homo sapiens

PMID:

33597510

Title:

Heparanase induces necroptosis of microvascular endothelial cells to promote the metastasis of hepatocellular carcinoma

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Mol Cell Biochem

Application:

IF:

3.396

Species:

Rattus norvegicus

PMID:

33608832

Title:

Intermittent high glucose induces pyroptosis of rat H9C2 cardiomyocytes via sodium-glucose cotransporter 1

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Mol Med Rep

Application:

IF:

2.952

Species:

Mus musculus

PMID:

34132358

Title:

MicroRNA?16?5p/BIMP1/NF?κB axis regulates autophagy to exert a tumor?suppressive effect on bladder cancer

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Int J Mol Med

Application:

IF:

4.101

Species:

Mus musculus

PMID:

34751408

Title:

BAY61?3606 attenuates neuroinflammation and neurofunctional damage by inhibiting microglial Mincle/Syk signaling response after traumatic brain injury

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Nutrients

Application:

IF:

6.7

Species:

Mus musculus

PMID:

36235742

Title:

Protective Effect of Rhus chinensis Mill. Fruits on 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine-Induced Cholestasis in Mice via Ameliorating Oxidative Stress and Inflammation - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Life sciences

Application:

IHC

IF:

6.78

Species:

Rattus norvegicus

PMID:

36209830

Title:

Agmatine-mediated inhibition of NMDA receptor expression and amelioration of dyskinesia via activation of Nrf2 and suppression of HMGB1/RAGE/TLR4/MYD88/NF …

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Journal of ethnopharmacology

Application:

IF:

5.19

Species:

Rattus norvegicus

PMID:

36228892

Title:

Efficacy of curculigoside in protecting against ischemic brain injury through regulation of oxidative stress and NF-κB and PI3K/Akt expression

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Application:

IF:

7.41

Species:

Homo sapiens

PMID:

35785707

Title:

Trichodermin inhibits the growth of oral cancer through apoptosis-induced mitochondrial dysfunction and HDAC-2-mediated signaling

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Food & function

Application:

IF:

6.31

Species:

Mus musculus

PMID:

35260874

Title:

Lycopene Ameliorates Atrazine-Induced Pyroptosis in Spleen via Suppressing the Ox-mtDNA/Nlrp3 Inflammasome Pathway

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

International journal of molecular sciences

Application:

IF:

6.2

Species:

Homo sapiens

PMID:

36232498

Title:

The Extracts of Dendrobium Alleviate Dry Eye Disease in Rat Model by Regulating Aquaporin Expression and MAPKs/NF-κB Signalling - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Drug design, development and therapy

Application:

IHC

IF:

4.31

Species:

Rattus norvegicus

PMID:

36105322

Title:

Alpha-Chymotrypsin Protects Against Acute Lung, Kidney, and Liver Injuries and Increases Survival in CLP-Induced Sepsis in Rats Through Inhibition of TLR4/NF-κB Pathway - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Pharmaceuticals (Basel, Switzerland)

Application:

IHC

IF:

5.21

Species:

Rattus norvegicus

PMID:

35893742

Title:

Activation of SIRT-1 Pathway by Nanoceria Sheds Light on Its Ameliorative Effect on Doxorubicin-Induced Cognitive Impairment (Chemobrain): Restraining Its Neuroinflammation, Synaptic Dysplasticity and Apoptosis - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Molecular neurobiology

Application:

IF:

5.68

Species:

Homo sapiens

PMID:

36053436

Title:

Isobavachalcone's Alleviation of Pyroptosis Contributes to Enhanced Apoptosis in Glioblastoma: Possible Involvement of NLRP3

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Medicina (Kaunas, Lithuania)

Application:

IF:

2.94

Species:

Homo sapiens

PMID:

35744061

Title:

The Therapeutic Role of PNU-74654 in Hepatocellular Carcinoma May Involve Suppression of NF-κB Signaling - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Frontiers in pharmacology

Application:

IF:

5.98

Species:

Mus musculus

PMID:

35662701

Title:

Calf Thymus Polypeptide Restrains the Growth of Colorectal Tumor via Regulating the Intestinal Microbiota-Mediated Immune Function - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

International journal of molecular sciences

Application:

IHC

IF:

6.2

Species:

Rattus norvegicus

PMID:

36361584

Title:

Methotrexate-Induced Alteration of Renal Aquaporins 1 and 2, Oxidative Stress and Tubular Apoptosis Can Be Attenuated by Omega-3 Fatty Acids Supplementation - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Brain sciences

Application:

IF:

3.33

Species:

Rattus norvegicus

PMID:

36552192

Title:

Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Journal of ethnopharmacology

Application:

IF:

5.19

Species:

Mus musculus

PMID:

36608779

Title:

Potential Anti-Gout Properties of Wuwei Shexiang Pills Based on Network Pharmacology and Pharmacological Verification

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Burns & trauma

Application:

IF:

5.71

Species:

Mus musculus

PMID:

36568527

Title:

Puerarin improves diabetic wound healing via regulation of macrophage M2 polarization phenotype - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Cell communication and signaling : CCS

Application:

IF:

7.52

Species:

Mus musculus

PMID:

36717921

Title:

Semaphorin 7A interacts with nuclear factor NF-kappa-B p105 via integrin β1 and mediates inflammation - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Oxidative medicine and cellular longevity

Application:

IF:

7.31

Species:

Mus musculus

PMID:

36865346

Title:

Aldehyde Dehydrogenase 2 Protects the Kidney from Ischemia-Reperfusion Injury by Suppressing the IκBα/NF-κB/IL-17C Pathway - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Frontiers in neuroanatomy

Application:

IHC

IF:

3.54

Species:

Rattus norvegicus

PMID:

36968023

Title:

Suppression of neuronal apoptosis and glial activation with modulation of Nrf2/HO-1 and NF-kB signaling by curcumin in streptozotocin-induced diabetic spinal cord central neuropathy - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Toxicology

Application:

IF:

4.57

Species:

Mus musculus

PMID:

36696940

Title:

PK2/PKRs pathway is involved in the protective effect of artemisinin against trimethyltin chloride-induced hippocampal injury

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Food & function

Application:

IF:

6.31

Species:

Mus musculus

PMID:

36786681

Title:

Confusoside, a dihydrochalcone glucoside, prevents acetaminophen-induced liver injury by modulating the Keap1-Nrf2/Nf-κB/Caspase signaling pathway

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Life Sci

Application:

WB, IHC

IF:

6.1

Species:

Mus musculus

PMID:

36640900

Title:

The novel TAK1 inhibitor handelin inhibits NF-κB and AP-1 activity to alleviate elastase-induced emphysema in mice

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Experimental and therapeutic medicine

Application:

IF:

2.75

Species:

Mus musculus

PMID:

37153898

Title:

Alleviating effect of lycorine on CFA-induced arthritic pain via inhibition of spinal inflammation and oxidative stress - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Molecular medicine (Cambridge, Mass.)

Application:

IF:

6.37

Species:

Mus musculus

PMID:

37528397

Title:

HOXA1 participates in VSMC-to-macrophage-like cell transformation via regulation of NF-κB p65 and KLF4: a potential mechanism of atherosclerosis pathogenesis - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Cellular immunology

Application:

IF:

4.17

Species:

Homo sapiens

PMID:

37210768

Title:

Downregulation of HHLA2 inhibits ovarian cancer progression via the NF-B signaling pathway and suppresses the expression of CA9

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Aging

Application:

IF:

5.95

Species:

Homo sapiens

PMID:

37589506

Title:

TNFR2 promotes pancreatic cancer proliferation, migration, and invasion via the NF-B signaling pathway - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Cell biochemistry and biophysics

Application:

IF:

2.98

Species:

Rattus norvegicus

PMID:

37735328

Title:

Fluorofenidone Attenuates Renal Interstitial Fibrosis by Enhancing Autophagy and Retaining Mitochondrial Function

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Journal of ethnopharmacology

Application:

IF:

5.19

Species:

Mus musculus

PMID:

37852335

Title:

Kuijie decoction ameliorates ulcerative colitis by affecting intestinal barrier functions, gut microbiota, metabolic pathways and Treg/Th17 balance in mice

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Journal of ethnopharmacology

Application:

IF:

5.19

Species:

Rattus norvegicus

PMID:

37659757

Title:

Analysis of pharmacodynamic components, targets and synergistic action mechanism of Fuyuan Shenghua granule for the treatment of medical-induced incomplete

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

International journal of biological macromolecules

Application:

IF:

8.02

Species:

pearl oyster

PMID:

37739291

Title:

The regulatory effect of NF-B signaling pathway on biomineralization and shell regeneration in pearl oyster, Pinctada fucata

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

European journal of nutrition

Application:

IF:

4.86

Species:

Mus musculus

PMID:

37460822

Title:

Prebiotics modulate the microbiotagutbrain axis and ameliorate cognitive impairment in APP/PS1 mice

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Journal of ethnopharmacology

Application:

IF:

5.19

Species:

Mus musculus

PMID:

37453619

Title:

'Pterocephalodes hookeri-Onosma hookeri'decoction protects against LPS-induced pulmonary inflammation via inhibiting TLR4/NF-B signaling pathway

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

British Journal of Pharmacology

Application:

IF:

7.3

Species:

Rattus norvegicus

PMID:

37485568

Title:

Inhibition of Brd4 alleviates osteoarthritis pain via suppression of neuroinflammation and activation of Nrf2mediated antioxidant signaling

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Cell Death Dis

Application:

IF:

9.685

Species:

Homo sapiens, Mus musculus

PMID:

34108444

Title:

SLC7A2 deficiency promotes hepatocellular carcinoma progression by enhancing recruitment of myeloid-derived suppressors cells

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Annals of medicine

Application:

IF:

5.34

Species:

Mus musculus

PMID:

37967241

Title:

Mechanisms of resveratrol against diabetic wound by network pharmacology and experimental validation - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Diabetology & metabolic syndrome

Application:

IF:

5.39

Species:

Homo sapiens

PMID:

37280692

Title:

Silencing LncRNA SNHG16 suppresses the diabetic inflammatory response by targeting the miR-212-3p/NF-B signaling pathway - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Aging

Application:

IF:

5.95

Species:

Homo sapiens

PMID:

37086261

Title:

Melatonin induces cell cycle arrest and suppresses tumor invasion in urinary bladder urothelial carcinoma - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

ACS nano

Application:

IF:

18.02

Species:

Homo sapiens

PMID:

37120837

Title:

Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

ACS nano

Application:

IF:

18.02

Species:

Homo sapiens

PMID:

37120837

Title:

Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Science advances

Application:

IF:

14.95

Species:

Rattus norvegicus

PMID:

38117891

Title:

An injectable and adaptable hydrogen sulfide delivery system for modulating neuroregenerative microenvironment - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Ecotoxicology and environmental safety

Application:

IF:

7.12

Species:

Sus scrofa

PMID:

38035519

Title:

Tanshinone IIA protects intestinal epithelial cells from deoxynivalenol-induced pyroptosis

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Bulletin of experimental biology and medicine

Application:

IF:

0.73

Species:

Homo sapiens

PMID:

36602602

Title:

BCL11B Upregulates the Expression of RelA in T Cells Stimulated with Staphylococcal Enterotoxin A

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Bioactive materials

Application:

IF:

16.87

Species:

Mus musculus

PMID:

38318229

Title:

Enzyme-like biomimetic oral-agent enabling modulating gut microbiota and restoring redox homeostasis to treat inflammatory bowel disease - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Journal of hazardous materials

Application:

IF:

14.22

Species:

Mus musculus

PMID:

38101018

Title:

Ozone Exposure Affects Corneal Epithelial Fate by Promoting mtDNA Leakage and cGAS/STING Activation

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

ChemMedChem

Application:

IF:

3.54

Species:

Mus musculus

PMID:

37815017

Title:

Design of novel balanced COX inhibitors based on natural antiinflammatory ascidian metabolites and celecoxib

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

J Neuroimmune Pharmacol

Application:

IF:

7.285

Species:

Mus musculus

PMID:

34727296

Title:

STING/NF-B/IL-6-Mediated Inflammation in Microglia Contributes to Spared Nerve Injury (SNI)-Induced Pain Initiation

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Experimental cell research

Application:

WB, IF

IF:

4.14

Species:

Rattus norvegicus

PMID:

28988741

Title:

Smad7 alleviates glomerular mesangial cell proliferation via the ROS-NF-B pathway

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Journal of biochemical and molecular toxicology

Application:

WB, IF

IF:

3.56

Species:

Rattus norvegicus

PMID:

36184831

Title:

Emodin suppresses oxaliplatininduced neuropathic pain by inhibiting COX2/NFB mediated spinal inflammation

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Neural plasticity

Application:

IF:

3.14

Species:

Rattus norvegicus

PMID:

36910013

Title:

Electroacupuncture Zusanli (ST36) Relieves Somatic Pain in Colitis Rats by Inhibiting Dorsal Root Ganglion Sympathetic-Sensory Coupling and Neurogenic Inflammation - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Acta tropica

Application:

IF, IP

IF:

3.22

Species:

Mus musculus

PMID:

35963313

Title:

Toxoplasma gondii rhoptry protein (TgROP18) enhances the expression of pro-inflammatory factor in LPS/IFN--induced murine BV2 microglia cells via NF-B signal

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Journal of agricultural and food chemistry

Application:

IF:

5.89

Species:

Rattus norvegicus

PMID:

35687823

Title:

Rosmarinic Acid Inhibits Platelet Aggregation and Neointimal Hyperplasia In Vivo and Vascular Smooth Muscle Cell Dedifferentiation, Proliferation, and Migration In

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Experimental animals

Application:

WB, IF

IF:

1.79

Species:

Mus musculus, Rattus norvegicus

PMID:

36740252

Title:

FERMT1 knockdown attenuates inflammation induced by intracerebral hemorrhage in rats via NLRP3/NF-B pathway

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Iranian journal of basic medical sciences

Application:

IHC

IF:

2.53

Species:

Rattus norvegicus

PMID:

36474570

Title:

TLR4-IN-C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-b axis, MAPK, and apoptosis - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Pharmaceuticals (Basel, Switzerland)

Application:

WB, IF

IF:

5.21

Species:

Mus musculus

PMID:

36558977

Title:

ATL I, Acts as a SIRT6 Activator to Alleviate Hepatic Steatosis in Mice via Suppression of NLRP3 Inflammasome Formation - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

International journal of molecular sciences

Application:

ELISA, WB, IHC

IF:

6.2

Species:

Mus musculus

PMID:

37569344

Title:

Aloe-Emodin Ameliorates Cecal Ligation and Puncture-Induced Sepsis

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

International journal of biological sciences

Application:

IF:

9.2

Species:

Homo sapiens

PMID:

38481798

Title:

Apigenin targets fetuin-A to ameliorate obesity-induced insulin resistance - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Experimental gerontology

Application:

IF:

3.9

Species:

Mus musculus

PMID:

38522309

Title:

Chuanzhitongluo capsule improves cognitive impairment in mice with chronic cerebral hypoperfusion via the cholinergic anti-inflammatory pathway

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Journal of neurosurgical anesthesiology

Application:

IF:

3.7

Species:

Mus musculus

PMID:

38577840

Title:

Morphine Preconditioning Alleviates Ischemia/Reperfusion-induced Caspase-8dependent Neuronal Apoptosis through cPKC-NF-B-cFLIPL Pathway

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

International journal of biological sciences

Application:

IF:

10.75

Species:

Mus musculus

PMID:

37928255

Title:

Genipin-activating PPAR impedes CCR2-mediated macrophage infiltration into postoperative liver to suppress recurrence of hepatocellular carcinoma - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

International journal of biological sciences

Application:

ChIP

IF:

10.75

Species:

Mus musculus

PMID:

37928255

Title:

Genipin-activating PPAR impedes CCR2-mediated macrophage infiltration into postoperative liver to suppress recurrence of hepatocellular carcinoma - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Journal of cellular and molecular medicine

Application:

IF:

5.3

Species:

Rattus norvegicus

PMID:

38693854

Title:

Improved therapeutic effects on vascular intimal hyperplasia by mesenchymal stem cells expressing MIR155HG that function as a ceRNA for microRNA-205 - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Frontiers in pharmacology

Application:

IF:

5.6

Species:

Rattus norvegicus

PMID:

38720773

Title:

Ganoderma lucidum spore extract improves sleep disturbances in a rat model of sporadic Alzheimers disease - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Oncology letters

Application:

IF:

3.11

Species:

Homo sapiens

PMID:

37153055

Title:

SHCBP1 contributes to the proliferation and self-renewal of cervical cancer cells and activation of the NF-B signaling pathway through EIF5A - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

iScience

Application:

IF:

5.8

Species:

Danio rerio,Mus musculus

PMID:

38766355

Title:

Mycobacterial CpsA activates type I IFN signaling in macrophages via cGAS-mediated pathway - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Environmental toxicology

Application:

RT-PCR, WB

IF:

4.5

Species:

Rattus norvegicus

PMID:

38651543

Title:

Betaine ameliorates doxorubicininduced cardiomyopathy by inhibiting oxidative stress, inflammation, and fibrosis through the modulation of AMPK/Nrf2/TGF

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Immunopharmacology and immunotoxicology

Application:

IF:

3.3

Species:

Mus musculus

PMID:

38772618

Title:

Anti-inflammatory effect of proanthocyanidins from blueberry through NF-B/NLRP3 signaling pathway in vivo and in vitro

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Cell biology and toxicology

Application:

IF:

6.1

Species:

Homo sapiens

PMID:

39042313

Title:

PD-L2 mediates tobacco smoking-induced recruitment of regulatory T cells via the RGMB/NFB/CCL20 cascade - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Journal of ethnopharmacology

Application:

IF:

5.4

Species:

Homo sapiens

PMID:

38925322

Title:

Efficacy and mechanism of action of Yanxiao Di'naer formula for non-alcoholic steatohepatitis treatment based on metabolomics and RNA sequencing

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Acta biomaterialia

Application:

IF:

9.7

Species:

Rattus norvegicus

PMID:

38761961

Title:

Pleiotropic effects of nitric oxide sustained-release system for peripheral nerve repair

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Application:

IF:

4.8

Species:

Rattus norvegicus

PMID:

38948938

Title:

Aerobic training attenuates cardiac remodeling in mice postmyocardial infarction by inhibiting the p300/CBPassociated factor

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

The Journal of toxicological sciences

Application:

IF:

Species:

Homo sapiens

PMID:

38945842

Title:

Dihydropyrazine induces endoplasmic reticulum stress and inhibits autophagy in HepG2 human hepatoma cells

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

iScience

Application:

IF:

5.8

Species:

Mus musculus

PMID:

39109172

Title:

Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

PLoS pathogens

Application:

IF:

6.7

Species:

Homo sapiens,Mus musculus

PMID:

39102426

Title:

SARS-CoV-2 spike-induced syncytia are senescent and contribute to exacerbated heart failure - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Nucleic acids research

Application:

Co-IP, WB

IF:

14.9

Species:

Drosophila melanogaster

PMID:

38742642

Title:

NF-B factors cooperate with Su(Hw)/E4F1 to balance Drosophila/human immune responses via modulating dynamic expression of miR-210

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Journal of virology

Application:

IF:

5.4

Species:

Homo sapiens

PMID:

38775480

Title:

GRP78 recognizes EV-F 3D protein and activates NF-B to repress virus replication by interacting with CHUK/IKBKB

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Application:

IF:

24.3

Species:

Homo sapiens

PMID:

37647746

Title:

Cell membrane-camouflaged bufalin targets NOD2 and overcomes multidrug resistance in pancreatic cancer

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Frontiers in microbiology

Application:

IF:

5.2

Species:

Mus musculus

PMID:

39282561

Title:

Administration of turmeric kombucha ameliorates lipopolysaccharide-induced sepsis by attenuating inflammation and modulating gut microbiota - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Application:

IF:

15.1

Species:

Mus musculus

PMID:

39258810

Title:

A MultiFunctional Nanoadjuvant Coupling Manganese with TollLike 9 Agonist Stimulates Potent Innate and Adaptive AntiTumor Immunity - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Cell biology and toxicology

Application:

IF, WB

IF:

6.1

Species:

Mus musculus

PMID:

39460844

Title:

CTRP9 attenuates peripheral nerve injury-induced mechanical allodynia and thermal hyperalgesia through regulating spinal microglial polarization and neuroinflammation mediated by AdipoR1 in male mice - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Cells

Application:

IF:

7.7

Species:

Homo sapiens

PMID:

39451232

Title:

NPS-1034 Exerts Therapeutic Efficacy in Renal Cell Carcinoma Through Multiple Targets of MET, AXL, and TNFRSF1A Signaling in a Metastatic Model - PMC

References for [KO Validated] NF-kB p65/RelA Rabbit mAb (A19653)

Product:

[KO Validated] NF-kB p65/RelA Rabbit mAb

Journal:

Gut microbes

Application:

IF:

12.2

Species:

Mus musculus

PMID:

39410876

Title:

High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis - PMC