제품 > 항체 > 다중클론항체(pAb)

β-Catenin Rabbit pAb (A11932)

Tested applications:WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP InhibitionReactivity:Human, Mouse, Rat

Western blot analysis of various lysates using β-Catenin Rabbit pAb (A11932) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.

ABclonal:Immunofluorescence - β-Catenin Rabbit pAb (A11932)

Immunofluorescence analysis of U2OS cells using β-Catenin Rabbit pAb (A11932) at dilution of 1:100. Blue: DAPI for nuclear staining.

Review

Overview

Product name	β-Catenin Rabbit pAb
Catalog No.	A11932
Host species	Rabbit
Purification method	Affinity purification
Isotype	IgG

Background

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

Immunogen information

Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human beta Catenin (NP_001895.1).
Sequence	MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFP
Gene ID
Swiss Prot
Synonyms	EVR7; CTNNB; MRD19; NEDSDV; armadillo; β-Catenin
Calculated MW	85kDa
Observed MW	100kDa

Applications

Reactivity	Human, Mouse, Rat
Tested applications	WB IHC-P IF/ICC IP ChIP ChIP-seq RIP FC FC(Intra)ELISA MeDIP Nucleotide Array DB FACS CoIP CUT&Tag meRIP Inhibition
Recommended dilution	WB 1:500 - 1:1000 IHC-P 1:50 - 1:200 IF/ICC 1:50 - 1:100
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Key application	Western blotting Immunohistochemistry Immunofluorescence
Positive samples	Mouse brain, Rat brain
Cellular location	Cell junction, Cell membrane, Cytoplasm, Nucleus, adherens junction, centrosome, cytoskeleton, microtubule organizing center, spindle pole.
Customer validation	(Mouse colon) WB(Mus musculus, Rattus norvegicus, Homo sapiens) IF(Mus musculus) IHC(Mus musculus) IHC(Mus musculus)

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Research Area

β-Catenin Rabbit pAb images

Western blot - β-Catenin Rabbit pAb (A11932)

Immunofluorescence - β-Catenin Rabbit pAb (A11932)

Immunofluorescence analysis of U2OS cells using β-Catenin Rabbit pAb (A11932) at dilution of 1:100. Blue: DAPI for nuclear staining.

* For research use only. Not for therapeutic or diagnostic purposes.

Submit an review for A11932

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Reviews List

Product Protocols

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

Cell

Application:

IF:

41.582

Species:

Mus musculus

PMID:

31585088

Title:

Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

Toxicology Letters

Application:

IF:

4.372

Species:

Rattus norvegicus

PMID:

31811911

Title:

Prenatal ethanol exposure increased the susceptibility of adult offspring rats to glomerulosclerosis

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

Cancer Lett

Application:

IF:

8.679

Species:

Mus musculus

PMID:

32920199

Title:

Knock down of BMSC-derived Wnt3a or its antagonist analogs attenuate colorectal carcinogenesis induced by chronic Fusobacterium nucleatum infection

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

Acta Pharmacol Sin

Application:

IF:

6.15

Species:

Rattus norvegicus

PMID:

33976388

Title:

Brexpiprazole caused glycolipid metabolic disorder by inhibiting GLP1/GLP1R signaling in rats

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

Antioxidants (Basel)

Application:

IF:

6.312

Species:

Mus musculus

PMID:

34198832

Title:

Procyanidin B2 Reduces Vascular Calcification through Inactivation of ERK1/2-RUNX2 Pathway

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

J Cancer

Application:

IF:

4.207

Species:

Mus musculus

PMID:

34659548

Title:

Bai-He-Gu-Jin-Tang formula suppresses lung cancer via AKT/GSK3β/β-catenin and induces autophagy via the AMPK/mTORC1/ULK1 signaling pathway

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

Frontiers in bioscience (Landmark edition)

Application:

IF:

3.11

Species:

Mus musculus

PMID:

37919087

Title:

Novel Indolyl-Benzimidazole Compounds Promote in vitro Wound Healing and Osteogenic Differentiation of Pluripotent Cells

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

International immunopharmacology

Application:

WB, IHC

IF:

5.714

Species:

Mus musculus

PMID:

29656209

Title:

Phosphorylation of low density lipoprotein receptor-related protein 6 is involved in receptor for advanced glycation end product-mediated -catenin stabilization in a toluene diisocyanate-induced asthma model

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

Cell biology and toxicology

Application:

IF:

6.1

Species:

Homo sapiens

PMID:

38691186

Title:

Retinoic acid mitigates the NSC319726-induced spermatogenesis dysfunction through cuproptosis-independent mechanisms - PMC

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

FEBS letters

Application:

IF:

3.5

Species:

Homo sapiens

PMID:

29364502

Title:

ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

FEBS Open Bio

Application:

IHC

IF:

2.6

Species:

Mus musculus

PMID:

30524946

Title:

Interleukin-18 expression in oral squamous cell carcinoma: its role in tumor cell migration and invasion, and growth of tumor cell xenografts.

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Application:

IF:

4.9

Species:

Rattus norvegicus

PMID:

32068029

Title:

Berberine encapsulated PEG-coated liposomes attenuate Wnt1/-catenin signaling in rheumatoid arthritis via miR-23a activation

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

International Immunopharmacology

Application:

IF:

5.6

Species:

Rattus norvegicus

PMID:

32088641

Title:

MiR-145-5p mitigates dysregulated Wnt1/-catenin signaling pathway in rheumatoid arthritis

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

Journal of cellular biochemistry

Application:

IF:

Species:

Homo sapiens

PMID:

30681184

Title:

Adipose mesenchymal stem cell-derived exosomes promote cell proliferation, migration, and inhibit cell apoptosis via Wnt/-catenin signaling in cutaneous wound healing.

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

Brain research bulletin

Application:

IF:

3.8

Species:

Rattus norvegicus

PMID:

31029599

Title:

The effect of lithium chloride on the attenuation of cognitive impairment in experimental hypoglycemic rats.

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

Journal of orthopaedic surgery and research

Application:

IF:

2.6

Species:

Rattus norvegicus

PMID:

39350234

Title:

Shuanglongjiegu pill promoted bone marrow mesenchymal stem cell osteogenic differentiation by regulating the miR-217/RUNX2 axis to activate Wnt/-catenin pathway - PMC

References for β-Catenin Rabbit pAb (A11932)

Product:

β-Catenin Rabbit pAb

Journal:

Experimental neurology

Application:

IF:

5.3

Species:

Mus musculus

PMID:

32991932